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The DotNetNuke content management system is intended to allow management of websites without much technical language, and to be extensible through a large number of third-party apps to provide functionality not included in the DotNetNuke core modules.
Skins can be used to change the look of a website using DotNetNuke.
The DotNetNuke Corporation is the steward of the DotNetNuke open source project. The open source version of DotNetNuke is called the Community Edition and is available as a free download. The Community Edition includes access to the source code of the framework and standard installation modules, and an MIT license  allowing modification and distribution rights. The Community Edition is a popular web content management (WCM) system and application development framework for ASP.NET, with over 6,000,000 downloads and 600,000 production web sites as of October 2010.
nopCommerce is a fully customizable shopping cart. It’s stable and highly usable. nopCommerce is an open source e-commerce solution that is ASP.NET 4.0 based with a MS SQL 2005 (or higher) backend database. Our easy-to-use shopping cart solution is uniquely suited for merchants that have outgrown existing systems, and may be hosted with your current web host or our hosting partners. It has everything you need to get started in selling physical and digital goods over the internet.